Munch Lab

Recombination in great ape evolution

I just received funding to support a research project on the evolution and mechanisms of recombination in the great apes.  Genetic recombination is integral to the evolution of species. It shuffles genetic variants to allow organisms to adapt by exposing individual properties of genetic variants to natural selection. Despite its immense importance little is known about the mechanisms that control recombination and how these evolve. In a recent publication we have shown that it is possible to infer recombination in ancestral species. The funded project will measure recombination in all living and ancestral species of great apes – and thereby measure the evolution of recombination along each branch in the entire great ape species tree. This new comparative approach will allow us to directly link the evolutionary change in the genomic sequence to the evolutionary change in recombination patterns and thereby generate new insight into how the genome sequence controls recombination and how the mechanism of this control evolves.

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out /  Change )

Google+ photo

You are commenting using your Google+ account. Log Out /  Change )

Twitter picture

You are commenting using your Twitter account. Log Out /  Change )

Facebook photo

You are commenting using your Facebook account. Log Out /  Change )

w

Connecting to %s

%d bloggers like this: