Munch Lab

Selective sweeps across twenty million years of primate evolution

Our paper in MBE shows how patterns of incomplete lineage sorting measures linked selection on evolutionary timescales. We show that a large portion of linked selection is due to selective sweeps and that the human-chimpanzee ancestor experienced a substantially higher frequency of sweeps than did the human-orangutang ancestor. These ancestral sweeps are enriched for sweeps in modern humans suggesting that several regions of the genome are repeatedly hit by sweeps.

Link to paper

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